Nuclear factor κB (NF-κB)–mediated inflammation in multiple sclerosis
Y Zhou, C Cui, X Ma, W Luo, SG Zheng… - Frontiers in …, 2020 - frontiersin.org
The nuclear factor κB (NF-κB) signaling cascade has been implicating in a broad range of
biological processes, including inflammation, cell proliferation, differentiation, and apoptosis.
The past three decades have witnessed a great progress in understanding the impact of
aberrant NF-κB regulation on human autoimmune and inflammatory disorders. In this
review, we discuss how aberrant NF-κB activation contributes to multiple sclerosis, a typical
inflammatory demyelinating disease of the central nervous system, and its involvement in …
biological processes, including inflammation, cell proliferation, differentiation, and apoptosis.
The past three decades have witnessed a great progress in understanding the impact of
aberrant NF-κB regulation on human autoimmune and inflammatory disorders. In this
review, we discuss how aberrant NF-κB activation contributes to multiple sclerosis, a typical
inflammatory demyelinating disease of the central nervous system, and its involvement in …
The nuclear factor κB (NF-κB) signaling cascade has been implicating in a broad range of biological processes, including inflammation, cell proliferation, differentiation, and apoptosis. The past three decades have witnessed a great progress in understanding the impact of aberrant NF-κB regulation on human autoimmune and inflammatory disorders. In this review, we discuss how aberrant NF-κB activation contributes to multiple sclerosis, a typical inflammatory demyelinating disease of the central nervous system, and its involvement in developing potential therapeutic targets.
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