Intravenous bisphosphonate-related osteonecrosis of the jaw: bone scintigraphy as an early indicator
FS O'Ryan, S Khoury, W Liao, MM Han, RL Hui… - Journal of Oral and …, 2009 - Elsevier
PURPOSE: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is recognized as a
serious complication among patients receiving bisphosphonate therapy. However, methods
for early detection and identification of patients at risk for osteonecrosis of the jaw (ONJ)
need further investigation. The purpose of this study was to characterize BRONJ among
patients receiving intravenous bisphosphonates and to examine bone scintigraphy findings
that preceded manifestation of frank ONJ. MATERIALS AND METHODS: We identified all …
serious complication among patients receiving bisphosphonate therapy. However, methods
for early detection and identification of patients at risk for osteonecrosis of the jaw (ONJ)
need further investigation. The purpose of this study was to characterize BRONJ among
patients receiving intravenous bisphosphonates and to examine bone scintigraphy findings
that preceded manifestation of frank ONJ. MATERIALS AND METHODS: We identified all …