Epstein–Barr virus and cancer
PJ Farrell - Annual Review of Pathology: Mechanisms of …, 2019 - annualreviews.org
Epstein–Barr virus (EBV) contributes to about 1.5% of all cases of human cancer worldwide,
and viral genes are expressed in the malignant cells. EBV also very efficiently causes the
proliferation of infected human B lymphocytes. The functions of the viral proteins and small
RNAs that may contribute to EBV-associated cancers are becoming increasingly clear, and
a broader understanding of the sequence variation of the virus genome has helped to
interpret their roles. The improved understanding of the mechanisms of these cancers …
and viral genes are expressed in the malignant cells. EBV also very efficiently causes the
proliferation of infected human B lymphocytes. The functions of the viral proteins and small
RNAs that may contribute to EBV-associated cancers are becoming increasingly clear, and
a broader understanding of the sequence variation of the virus genome has helped to
interpret their roles. The improved understanding of the mechanisms of these cancers …