PfRH5 as a candidate vaccine for Plasmodium falciparum malaria
DR Drew, JG Beeson - Trends in parasitology, 2015 - cell.com
DR Drew, JG Beeson
Trends in parasitology, 2015•cell.comPfRH5 has recently emerged as a strong vaccine candidate for Plasmodium falciparum
malaria. Antibodies inhibit invasion of erythrocytes by merozoites and blood-stage
replication, and PfRH5 is a significant target of acquired human immunity. Recent studies
have shown protective efficacy of PfRH5 vaccines in a non-human primate model of malaria.
malaria. Antibodies inhibit invasion of erythrocytes by merozoites and blood-stage
replication, and PfRH5 is a significant target of acquired human immunity. Recent studies
have shown protective efficacy of PfRH5 vaccines in a non-human primate model of malaria.
PfRH5 has recently emerged as a strong vaccine candidate for Plasmodium falciparum malaria. Antibodies inhibit invasion of erythrocytes by merozoites and blood-stage replication, and PfRH5 is a significant target of acquired human immunity. Recent studies have shown protective efficacy of PfRH5 vaccines in a non-human primate model of malaria.
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