Mechanisms of disease of eosinophilic esophagitis
BP Davis, ME Rothenberg - Annual Review of Pathology …, 2016 - annualreviews.org
Annual Review of Pathology: Mechanisms of Disease, 2016•annualreviews.org
Eosinophilic esophagitis (EoE) is a recently recognized inflammatory disease of the
esophagus with clinical symptoms derived from esophageal dysfunction. The etiology of
EoE is now being elucidated, and food hypersensitivity is emerging as the central
cornerstone of disease pathogenesis. Herein, we present a thorough picture of the current
clinical, pathologic, and molecular understanding of the disease with a focus on disease
mechanisms.
esophagus with clinical symptoms derived from esophageal dysfunction. The etiology of
EoE is now being elucidated, and food hypersensitivity is emerging as the central
cornerstone of disease pathogenesis. Herein, we present a thorough picture of the current
clinical, pathologic, and molecular understanding of the disease with a focus on disease
mechanisms.
Eosinophilic esophagitis (EoE) is a recently recognized inflammatory disease of the esophagus with clinical symptoms derived from esophageal dysfunction. The etiology of EoE is now being elucidated, and food hypersensitivity is emerging as the central cornerstone of disease pathogenesis. Herein, we present a thorough picture of the current clinical, pathologic, and molecular understanding of the disease with a focus on disease mechanisms.
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