Background The threat of levodopa-induced dyskinesias often influences early treatment
decisions in those with Parkinson disease. Objective To determine the long-term risks of
levodopa-associated dyskinesias of any severity, dyskinesias sufficient to require
medication adjustment, and dyskinesias failing medication adjustments. Design The medical
records linkage system of the Rochester Epidemiology Project was used to identify all
incident Parkinson disease patients treated with levodopa (1976-1990). All records were …