[HTML][HTML] Insights into herpesvirus tegument organization from structural analyses of the 970 central residues of HSV-1 UL36 protein
N Scrima, J Lepault, Y Boulard, D Pasdeloup… - Journal of Biological …, 2015 - ASBMB
The tegument of all herpesviruses contains a capsid-bound large protein that is essential for
multiple viral processes, including capsid transport, decapsidation at the nuclear pore
complex, particle assembly, and secondary envelopment, through mechanisms that are still
incompletely understood. We report here a structural characterization of the central 970
residues of this protein for herpes simplex virus type 1 (HSV-1 UL36, 3164 residues). This
large fragment is essentially a 34-nm-long monomeric fiber. The crystal structure of its C …
multiple viral processes, including capsid transport, decapsidation at the nuclear pore
complex, particle assembly, and secondary envelopment, through mechanisms that are still
incompletely understood. We report here a structural characterization of the central 970
residues of this protein for herpes simplex virus type 1 (HSV-1 UL36, 3164 residues). This
large fragment is essentially a 34-nm-long monomeric fiber. The crystal structure of its C …