Glaucoma patients present increased levels of diadenosine tetraphosphate, Ap4A, in the aqueous humour
M Castany, I Jordi, J Catala, A Gual, M Morales… - Experimental eye …, 2011 - Elsevier
Previous studies have shown the presence of diadenosine tetraphosphate (Ap4A) and
pentaphosphate (Ap5A) in the aqueous humour (AH) of different species. When topically
applied to the rabbit cornea, Ap4A decreased IOP while Ap5A increased it. Here we study
the presence of dinucleoside polyphosphates in the AH from human patients with or without
glaucoma. AH was obtained at the time of cataract surgery from patients with (n= 16) or
without (n= 10) primary open-angle glaucoma. AH (0.1–0.2 ml) was collected at the …
pentaphosphate (Ap5A) in the aqueous humour (AH) of different species. When topically
applied to the rabbit cornea, Ap4A decreased IOP while Ap5A increased it. Here we study
the presence of dinucleoside polyphosphates in the AH from human patients with or without
glaucoma. AH was obtained at the time of cataract surgery from patients with (n= 16) or
without (n= 10) primary open-angle glaucoma. AH (0.1–0.2 ml) was collected at the …
