Raised plasma endothelin-I concentration following cold pressor test
F Fyhrquist, O Saijonmaa, K Metsärinne… - Biochemical and …, 1990 - Elsevier
F Fyhrquist, O Saijonmaa, K Metsärinne, I Tikkanen, K Rosenlöf, T Tikkanen
Biochemical and biophysical research communications, 1990•ElsevierPlasma concentration of immunoreactive endothelin-1 was measured by radioimmunoassay
in 6 healthy subjects before and following cold pressor test by immersion of one fore-arm
into icewater. Mean (SEM) plasma endothelin-1 concentration rose from 1.2 (0.7) to peak
value 8.4 (2.3) pg/ml in venous plasma from the immersed hand, and, reaching peak 2
minutes later, from 1.4 (0.5) to 4.6 (2.3) pg/ml in venous plasma from the contralateral hand.
In 66 healthy control subjects, venous plasma concentration of endothelin-1 was 2.9±1.2 …
in 6 healthy subjects before and following cold pressor test by immersion of one fore-arm
into icewater. Mean (SEM) plasma endothelin-1 concentration rose from 1.2 (0.7) to peak
value 8.4 (2.3) pg/ml in venous plasma from the immersed hand, and, reaching peak 2
minutes later, from 1.4 (0.5) to 4.6 (2.3) pg/ml in venous plasma from the contralateral hand.
In 66 healthy control subjects, venous plasma concentration of endothelin-1 was 2.9±1.2 …
Abstract
Plasma concentration of immunoreactive endothelin-1 was measured by radioimmunoassay in 6 healthy subjects before and following cold pressor test by immersion of one fore-arm into icewater. Mean (SEM) plasma endothelin-1 concentration rose from 1.2 (0.7) to peak value 8.4 (2.3) pg/ml in venous plasma from the immersed hand, and, reaching peak 2 minutes later, from 1.4 (0.5) to 4.6 (2.3) pg/ml in venous plasma from the contralateral hand. In 66 healthy control subjects, venous plasma concentration of endothelin-1 was 2.9 ± 1.2 pg/ml (mean ± SD). Exposure to cold is associated with raised blood levels of endothelin-1, which points to a relation between endothelin-1 and vasoconstriction associated with low temperature.
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