ABUNDANT EVIDENCE EXISTS IN BOTH ANIMALS AND humans with sepsis for the
appearance of a “cyto-kine storm,” characterized by high plasma levels of proinflammatory
cytokines and chemokines, 1 clinical signs of fever, tachycardia, and tachypnea and
followed rapidly by development of shock, multiorgan failure, and death. 2 Additional
evidence indicates that sepsis can be associated with a state of immunosuppression,
broadly defined as lymphopenia and loss of immune function, though the timing, incidence …