Antinucleosome Antibodies: A Critical Reflection on Their Specificities and Diagnostic Impact.
OP Rekvig, J Vlag, N Seredkina - Arthritis & Rheumatology, 2014 - search.ebscohost.com
OP Rekvig, J Vlag, N Seredkina
Arthritis & Rheumatology, 2014•search.ebscohost.comThe article discusses a study that examined whether antinucleosome antibodies may be
used as a diagnostic tool in systemic lupus erythematosus and other autoimmune diseases.
Topics covered include the variation of tolerance to nucleosomes, the identification of
autoantibodies with analytical assays and examples of antibodies that are reactive to
nucleosomes. Also mentioned is the questionable results of the testing of antinucleosome
assays for use in diagnostics.
used as a diagnostic tool in systemic lupus erythematosus and other autoimmune diseases.
Topics covered include the variation of tolerance to nucleosomes, the identification of
autoantibodies with analytical assays and examples of antibodies that are reactive to
nucleosomes. Also mentioned is the questionable results of the testing of antinucleosome
assays for use in diagnostics.
Abstract
The article discusses a study that examined whether antinucleosome antibodies may be used as a diagnostic tool in systemic lupus erythematosus and other autoimmune diseases. Topics covered include the variation of tolerance to nucleosomes, the identification of autoantibodies with analytical assays and examples of antibodies that are reactive to nucleosomes. Also mentioned is the questionable results of the testing of antinucleosome assays for use in diagnostics.
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