Fecal microbiota transplantation in the management of hepatic encephalopathy
Discussion To our knowledge, this is the first report of treating HE with FMT. In this case, the
dramatic clinical improvements, both subjectively and objectively, following serial FMT are
very encouraging. Previous studies have shown Lachnospiraceae to be linked with good
cognitive performance. 4 In this case, despite a reduction in relative abundance of
Lachnospiraceae following FMT, there was an obvious improvement in his cognition,
suggesting that other microbial taxa and metabolic activity are involved. The lack of …
dramatic clinical improvements, both subjectively and objectively, following serial FMT are
very encouraging. Previous studies have shown Lachnospiraceae to be linked with good
cognitive performance. 4 In this case, despite a reduction in relative abundance of
Lachnospiraceae following FMT, there was an obvious improvement in his cognition,
suggesting that other microbial taxa and metabolic activity are involved. The lack of …