Troponin T in spinal and bulbar muscular atrophy (SBMA)
G Musso, L Blasi, MM Mion, A Fortuna… - Journal of the …, 2024 - Elsevier
Serum biomarkers that might detect clinical progression are currently lacking for Spinal and
bulbar muscular atrophy (SBMA), thus limiting the effectiveness of possible future
pharmacological trials. Elevation of cardiac troponin T (cTnT) unrelated to myocardial
damage in a motor neuron (MN) disease as amyotrophic lateral sclerosis (ALS) was
associated to disease severity. We enrolled 47 SBMA patients and 5 Spinal muscular
atrophy (SMA) type 3 adult patients as control group; each SBMA patient was evaluated at …
bulbar muscular atrophy (SBMA), thus limiting the effectiveness of possible future
pharmacological trials. Elevation of cardiac troponin T (cTnT) unrelated to myocardial
damage in a motor neuron (MN) disease as amyotrophic lateral sclerosis (ALS) was
associated to disease severity. We enrolled 47 SBMA patients and 5 Spinal muscular
atrophy (SMA) type 3 adult patients as control group; each SBMA patient was evaluated at …
