Vascular remodelling is an important physiological mechanism that occurs as a result of
changes in hemodynamics, and is a pathological process that plays a major role in the
clinical manifestations of cardiovascular diseases. Using a mouse model, it was recently
established that vascular remodelling is partially based on ligation of the carotid. In this
model, low flow was associated with intima media thickening (IMT). IMT is a major
manifestation of atherosclerosis of the carotid artery, and it is an important predictor of …