Mitochondria play an important role as an intracellular energy plant and signaling organelle.
However, mitochondria also exist outside cells where they could mediate cell-to-cell
communication, repair and serve as an activator of the immune response. Their effects
depend on the mitochondrial state or the form in which it is present, either as a whole
functional structure as fragments or only as mitochondrial DNA. Herein, we provide evidence
of why extracellular mitochondria and their varying forms are considered regenerative …