Cyclooxygenase-2 (cox-2) and the inflammogenesis of cancer

RE Harris - Inflammation in the Pathogenesis of Chronic Diseases …, 2007 - Springer
RE Harris
Inflammation in the Pathogenesis of Chronic Diseases: The COX-2 Controversy, 2007Springer
Cohesive scientific evidence from molecular, animal, and human investigations supports the
hypothesis that aberrant induction of COX-2 and up-regulation of the prostaglandin cascade
play a significant role in carcinogenesis, and reciprocally, blockade of the process has
strong potential for cancer prevention and therapy. Supporting evidence
Abstract
Cohesive scientific evidence from molecular, animal, and human investigations supports the hypothesis that aberrant induction of COX-2 and up-regulation of the prostaglandin cascade play a significant role in carcinogenesis, and reciprocally, blockade of the process has strong potential for cancer prevention and therapy. Supporting evidence
Springer