Therapeutic targets of human AKI: harmonizing human and animal AKI

MD Okusa, MH Rosner, JA Kellum… - Journal of the American …, 2016 - journals.lww.com
The opportunity to make advances in the prevention and treatment of AKI has never been
greater than it is today. Major advances have been made in the understanding of the biology
of AKI, the design of clinical trials, and the use of diagnostic and prognostic biomarkers.
These advances have been supplemented by the coordinated effort of societies, federal
agencies, and industry, such that we are poised in the ensuing years to positively address
the unrelenting harm that this disorder has created. Over the past decade, major advances …