Serum proteomics identifies biomarkers associated with the pathogenesis of idiopathic pulmonary fibrosis
L Wang, M Zhu, Y Li, P Yan, Z Li, X Chen… - Molecular & Cellular …, 2023 - mcponline.org
The heterogeneity of idiopathic pulmonary fibrosis (IPF) limits its diagnosis and treatment.
The association between the pathophysiological features and the serum protein signatures
of IPF currently remains unclear. The present study analyzed the specific proteins and
patterns associated with the clinical parameters of IPF based on a serum proteomic dataset
by data-independent acquisition using MS. Differentiated proteins in sera distinguished
patients with IPF into three subgroups in signal pathways and overall survival. Aging …
The association between the pathophysiological features and the serum protein signatures
of IPF currently remains unclear. The present study analyzed the specific proteins and
patterns associated with the clinical parameters of IPF based on a serum proteomic dataset
by data-independent acquisition using MS. Differentiated proteins in sera distinguished
patients with IPF into three subgroups in signal pathways and overall survival. Aging …
