Posttranscriptional and posttranslational regulation of BK channels
MJ Shipston, L Tian - International review of neurobiology, 2016 - Elsevier
Large conductance calcium-and voltage-activated potassium (BK) channels are ubiquitously
expressed and play an important role in the regulation of an eclectic array of physiological
processes. Their diverse functional role requires channels with a wide variety of properties
even though the pore-forming α-subunit is encoded by a single gene, KCNMA 1. To achieve
this, BK channels exploit some of the most fundamental posttranscriptional and
posttranslational mechanisms that allow proteomic diversity to be generated from a single …
expressed and play an important role in the regulation of an eclectic array of physiological
processes. Their diverse functional role requires channels with a wide variety of properties
even though the pore-forming α-subunit is encoded by a single gene, KCNMA 1. To achieve
this, BK channels exploit some of the most fundamental posttranscriptional and
posttranslational mechanisms that allow proteomic diversity to be generated from a single …
