[HTML][HTML] Dendritic cell therapies for hematologic malignancies

M Weinstock, J Rosenblatt, D Avigan - Molecular Therapy Methods & …, 2017 - cell.com
M Weinstock, J Rosenblatt, D Avigan
Molecular Therapy Methods & Clinical Development, 2017cell.com
Dendritic cells (DCs) are potent antigen-presenting cells that constitute a major component
of the immune system's role in the recognition, elimination, and tolerance of cancer. The
unique immunologic capabilities of DCs have recently been harnessed for therapeutic use
with the creation of DC-based anti-tumor vaccines, several of which have moved into testing
in clinical trials for hematologic malignancies. This review summarizes how treatment
strategies using DC-based anti-tumor vaccines are advancing immunotherapeutic options …
Dendritic cells (DCs) are potent antigen-presenting cells that constitute a major component of the immune system's role in the recognition, elimination, and tolerance of cancer. The unique immunologic capabilities of DCs have recently been harnessed for therapeutic use with the creation of DC-based anti-tumor vaccines, several of which have moved into testing in clinical trials for hematologic malignancies. This review summarizes how treatment strategies using DC-based anti-tumor vaccines are advancing immunotherapeutic options for these diseases.
cell.com