Virus-like particles associated with intracardiac ganglionitis in 2 cases of sudden unexpected death

TN James, K Imamura - Japanese Heart Journal, 1981 - jstage.jst.go.jp
TN James, K Imamura
Japanese Heart Journal, 1981jstage.jst.go.jp
Two previously healthy young individuals died suddenly and unexpectedly, and in both of
them there was gangloitis in the heart, especially near the sinus node. Electron microscopic
examination demonstrated virus-like particles in the vicinity of the ganglionitis of both hearts.
Viral card ioneuropathy may play a role in the pathogenesis of sudden unexpected deaths
and deserves further investigation.
Summary
Two previously healthy young individuals died suddenly and unexpectedly, and in both of them there was gangloitis in the heart, especially near the sinus node. Electron microscopic examination demonstrated virus-like particles in the vicinity of the ganglionitis of both hearts. Viral card ioneuropathy may play a role in the pathogenesis of sudden unexpected deaths and deserves further investigation.
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