[HTML][HTML] Liposcale: A novel advanced lipoprotein test based on 2D diffusion-ordered 1H NMR spectroscopy [S]
Determination of lipoprotein particle size and number using advanced lipoprotein tests
(ALTs) is of particular importance to improve cardiovascular risk prediction. Here we present
the Liposcale test, a novel ALT based on 2D diffusion-ordered 1 H NMR spectroscopy. Our
method uses diffusion coefficients to provide a direct measure of the mean particle sizes and
numbers. Using 177 plasma samples from healthy individuals and the concentration of
ApoB and ApoA from isolated lipoprotein fractions, our test showed a stronger correlation …
(ALTs) is of particular importance to improve cardiovascular risk prediction. Here we present
the Liposcale test, a novel ALT based on 2D diffusion-ordered 1 H NMR spectroscopy. Our
method uses diffusion coefficients to provide a direct measure of the mean particle sizes and
numbers. Using 177 plasma samples from healthy individuals and the concentration of
ApoB and ApoA from isolated lipoprotein fractions, our test showed a stronger correlation …