P-selectin/PSGL-1 inhibitors versus enoxaparin in the resolution of venous thrombosis: a meta-analysis
E Ramacciotti, DD Myers Jr, SK Wrobleski… - Thrombosis research, 2010 - Elsevier
BACKGROUND: P-selectin antagonism has been shown to decrease thrombogenesis and
inflammation in animal models of deep venous thrombosis (DVT). OBJECTIVE: To
determine the effectiveness of P-selectin inhibitors versus saline and enoxaparin in venous
thrombus resolution in nonhuman primate models of venous thrombosis. METHODS:
Studies reporting vein re-opening, inflammation expressed as Gadolinium enhancement
and coagulation parameters were searched in the literature and pooled into a meta-analysis …
inflammation in animal models of deep venous thrombosis (DVT). OBJECTIVE: To
determine the effectiveness of P-selectin inhibitors versus saline and enoxaparin in venous
thrombus resolution in nonhuman primate models of venous thrombosis. METHODS:
Studies reporting vein re-opening, inflammation expressed as Gadolinium enhancement
and coagulation parameters were searched in the literature and pooled into a meta-analysis …
