Evidence that endogenous catecholamines are involved inα2-adrenoceptor-mediated modulation of the aortic baroreceptor reflex in the nucleus tractus solitarii of the …
T Kubo, Y Goshima, H Hata, Y Misu - Brain research, 1990 - Elsevier
T Kubo, Y Goshima, H Hata, Y Misu
Brain research, 1990•ElsevierMicroinjections of α-methylnoradrenaline and tyramine into the rat nucleus tractus solitarii
(NTS) potentiated the depressor and bradycardic responses to aortic nerve stimulation
whereas yohimbine injected similarly inhibited them. NTS pretreatment with yohimbine
inhibited the baroreflex potentiation effects of α-methylnoradrenaline and tyramine whereas
intraventricular pretreatment with 6-hydroxydopamine inhibited only that of tyramine. These
results provide evidence that endogenous catecholamines in the rat NTS are involved in …
(NTS) potentiated the depressor and bradycardic responses to aortic nerve stimulation
whereas yohimbine injected similarly inhibited them. NTS pretreatment with yohimbine
inhibited the baroreflex potentiation effects of α-methylnoradrenaline and tyramine whereas
intraventricular pretreatment with 6-hydroxydopamine inhibited only that of tyramine. These
results provide evidence that endogenous catecholamines in the rat NTS are involved in …
Abstract
Microinjections of α-methylnoradrenaline and tyramine into the rat nucleus tractus solitarii (NTS) potentiated the depressor and bradycardic responses to aortic nerve stimulation whereas yohimbine injected similarly inhibited them. NTS pretreatment with yohimbine inhibited the baroreflex potentiation effects of α-methylnoradrenaline and tyramine whereas intraventricular pretreatment with 6-hydroxydopamine inhibited only that of tyramine. These results provide evidence that endogenous catecholamines in the rat NTS are involved in alpha2 adrenoceptor-mediated modulation of the aortic baroreceptor reflex.
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