Multinucleated spermatocytes and spermatids in human seminiferous tubules
AF Holstein, C Eckmann - Andrologia, 1986 - Wiley Online Library
AF Holstein, C Eckmann
Andrologia, 1986•Wiley Online LibraryThe cytology of multinucleated spermatocytes and spermatid giant cells in the seminiferous
tubules of men with oligozoospermia and of men older than 65 years has been investigated
electron microscopically. Two different processes which are responsible for the origin of
multinucleated germ cells have been analysed: 1. Defects of the intercellular bridges (IB):
they move apart and thus allow the confluence of one clone's cells to symplasms. 2. The
confluence of membranes: within one clone the membranes of neighbouring germ cells are …
tubules of men with oligozoospermia and of men older than 65 years has been investigated
electron microscopically. Two different processes which are responsible for the origin of
multinucleated germ cells have been analysed: 1. Defects of the intercellular bridges (IB):
they move apart and thus allow the confluence of one clone's cells to symplasms. 2. The
confluence of membranes: within one clone the membranes of neighbouring germ cells are …
Summary
The cytology of multinucleated spermatocytes and spermatid giant cells in the seminiferous tubules of men with oligozoospermia and of men older than 65 years has been investigated electron microscopically. Two different processes which are responsible for the origin of multinucleated germ cells have been analysed:
1. Defects of the intercellular bridges (IB): they move apart and thus allow the confluence of one clone's cells to symplasms.
2. The confluence of membranes: within one clone the membranes of neighbouring germ cells are dissolved and thus intercellular bridges are found in the cytoplasm of the resulting giant cells.
The spermatid giant cells reveal a new organization of the cell nuclei and the cell or‐ganelles. Yet they disintegrate in the lumen of the seminiferous tubules. The appearance of giant cells therefore is an expression of the germ cell degeneration.
Vielkemige Spermatozyten und Spermatiden in menschlichen Samenkanälchen
Zusammenfassung: Die Zytologie von mehrkemigen Spermatozyten und Spermatiden‐riesenzellen in Samenkanälchen von Männem mit Oligozoospermie und bei Männern, die älter als 65 Jahre sind, wird elektronenmikroskopisch untersucht. Für das Zustandekom‐men der mehrkemigen Keimzellen lassen sich zwei Vorgänge erkennen:
1. Defekte der Interzellularbrücken (IB): sie weichen auseinander und die Zellen eines Klon fließen zu Symplasmen zusammen.
2. Das Zusammenfließen benachbarter Zellmembranen der Zellen eines Keimzellklon: da‐durch werden die Interzellularbrücken in das Zytoplasma der so entstandenen Riesen‐zelle verlagert.
Die Spermatidenriesenzellen zeigen eine neue Organisation der Zellkeme und Zellorga‐neden, gehen letztlich aber zugrunde. Das Auftreten der Riesenzellen ist ein Ausdruck der Degeneration von Keimzellen.
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