At its October 2020 meeting, the Advisory Committee on Immunization Practices*(ACIP) approved the 2021 Recommended Child and Adolescent Immunization Schedule for Ages 18 Years or Younger. After Emergency Use Authorization of Pfizer-BioNTech COVID-19 vaccine by the Food and Drug Administration (FDA), ACIP issued an interim recommendation for use of Pfizer-BioNTech COVID-19 vaccine in persons aged≥ 16 years at its December 12, 2020, meeting (1). In addition, ACIP approved an amendment to include COVID-19 vaccine recommendations in the child and adolescent immunization schedule. After Emergency Use Authorization of Moderna COVID-19 vaccine by FDA, ACIP issued an interim recommendation for use of Moderna COVID-19 vaccine in persons aged≥ 18 years at its December 19, 2020, emergency meeting (2).

The 2021 child and adolescent immunization schedule summarizes ACIP recommendations, including several changes from the 2020 immunization schedule† on the cover page, two tables, and notes found on the CDC immunization schedule website (https://www. cdc. gov/vaccines/schedules). Health care providers are advised to use the tables and the notes together. This immunization schedule is recommended by ACIP (https://www. cdc. gov/vaccines/acip) and approved by CDC (https://www. cdc. gov), the American Academy of Pediatrics (https://www. aap. org external icon