Cartilaginous metaplasia in calcific aortic valve disease
DA Groom, WR Starke - American journal of clinical pathology, 1990 - academic.oup.com
DA Groom, WR Starke
American journal of clinical pathology, 1990•academic.oup.comIn a 49-year-old man, symptoms of aortic valve stenosis developed that required surgical
intervention with valve replacement. Pathologic examination of the valve showed severe
calcific aortic sclerosis and foci of hyaline cartilage. The authors believe that these foci are
secondary to cartilaginous transformation of mesenchymal valvular tissue. This represents
abnormal repair of valvular tissue damaged, in this case, by the nodular calcific process of
calcific aortic stenosis.
intervention with valve replacement. Pathologic examination of the valve showed severe
calcific aortic sclerosis and foci of hyaline cartilage. The authors believe that these foci are
secondary to cartilaginous transformation of mesenchymal valvular tissue. This represents
abnormal repair of valvular tissue damaged, in this case, by the nodular calcific process of
calcific aortic stenosis.
Abstract
In a 49-year-old man, symptoms of aortic valve stenosis developed that required surgical intervention with valve replacement. Pathologic examination of the valve showed severe calcific aortic sclerosis and foci of hyaline cartilage. The authors believe that these foci are secondary to cartilaginous transformation of mesenchymal valvular tissue. This represents abnormal repair of valvular tissue damaged, in this case, by the nodular calcific process of calcific aortic stenosis.
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