The pathology of influenza virus infections
JK Taubenberger, DM Morens - Annu. Rev. Pathol. Mech. Dis., 2008 - annualreviews.org
Influenza viruses are significant human respiratory pathogens that cause both seasonal,
endemic infections and periodic, unpredictable pandemics. The worst pandemic on record,
in 1918, killed approximately 50 million people worldwide. Human infections caused by
H5N1 highly pathogenic avian influenza viruses have raised concern about the emergence
of another pandemic. The histopathology of fatal influenza virus pneumonias as
documented over the past 120 years is reviewed here. Strikingly, the spectrum of pathologic …
endemic infections and periodic, unpredictable pandemics. The worst pandemic on record,
in 1918, killed approximately 50 million people worldwide. Human infections caused by
H5N1 highly pathogenic avian influenza viruses have raised concern about the emergence
of another pandemic. The histopathology of fatal influenza virus pneumonias as
documented over the past 120 years is reviewed here. Strikingly, the spectrum of pathologic …
