Healthy donor fecal microbiota transplantation in steroid-ineligible severe alcoholic hepatitis: a pilot study

CA Philips, A Pande, SM Shasthry… - Clinical …, 2017 - cghjournal.org
Methods Of 195 patients with alcoholic liver disease between December 2014 and February
2015, a total of 51 (26.1%) had SAH and 38 (75.7%) were steroid ineligible, mainly because
of sepsis or a recent upper gastrointestinal bleed. Eight male patients (mean model for end-
stage liver disease [MELD] score, 31±5.6; MELD-sodium, 33.6±4.3; Child-Turcotte-Pugh
score, 14±0.8; serum aspartate transaminase, 137±57 IU/mL) consented to FMT procedure.
Thirty grams of donor stool samples were obtained after stringent screening from consenting …