Inflammation, oxidative stress, and insulin resistance in polycystic kidney disease

V Menon, D Rudym, P Chandra… - Clinical Journal of the …, 2011 - journals.lww.com
Results The hypertensive ADPKD eGFR of 25 to 60 group had higher levels of C-reactive
protein and IL-6 than controls, normotensive ADPKD with eGFR of> 60, and hypertensive
ADPKD with eGFR of> 60. The normotensive ADPKD eGFR> 60, hypertensive ADPKD
eGFR> 60, and hypertensive ADPKD eGFR 25 to 60 groups had higher 8-epi-PGF 2α and
lower SOD than controls, with no difference between the ADPKD groups. There was no
difference in HOMA levels between any of the groups. Adjustment for age, race, gender, and …