Anatomical and physiological development of the human inner ear

R Lim, AM Brichta - Hearing research, 2016 - Elsevier
We describe the development of the human inner ear with the invagination of the otic vesicle
at 4 weeks gestation (WG), the growth of the semicircular canals from 5 WG, and the
elongation and coiling of the cochlea at 10 WG. As the membranous labyrinth takes shape,
there is a concomitant development of the sensory neuroepithelia and their associated
structures within. This review details the growth and differentiation of the vestibular and
auditory neuroepithelia, including synaptogenesis, the expression of stereocilia and …