Cochlear implantation in individuals with Usher type 1 syndrome
XZ Liu, SI Angeli, K Rajput, D Yan, AV Hodges… - International journal of …, 2008 - Elsevier
OBJECTIVE: To analyze the occurrence of the Usher type 1 (USH1) gene mutations in
cochlear implant recipients with deaf-blind Usher syndrome, and to assess the potential
effect of these genes and other factors on the therapeutic outcome. STUDY DESIGN: Case
series study of nine patients with the phenotypic diagnosis of USH1. METHODS AND
SUBJECTS: Mutation analysis of four USH1 genes (MYO7A, USH1C, CDH23, and
PCDH15) by single strand conformational polymorphism (SSCP) and direct sequencing …
cochlear implant recipients with deaf-blind Usher syndrome, and to assess the potential
effect of these genes and other factors on the therapeutic outcome. STUDY DESIGN: Case
series study of nine patients with the phenotypic diagnosis of USH1. METHODS AND
SUBJECTS: Mutation analysis of four USH1 genes (MYO7A, USH1C, CDH23, and
PCDH15) by single strand conformational polymorphism (SSCP) and direct sequencing …