Anti-MuSK antibodies: correlation with myasthenia gravis severity

E Bartoccioni, F Scuderi, GM Minicuci, M Marino… - Neurology, 2006 - AAN Enterprises
E Bartoccioni, F Scuderi, GM Minicuci, M Marino, F Ciaraffa, A Evoli
Neurology, 2006AAN Enterprises
The authors measured anti–muscle-specific tyrosine kinase (anti-MuSK) antibodies (Abs) in
83 serum samples from 40 patients and evaluated their correlation with myasthenia gravis
severity and treatment response. Ab concentrations were often reduced by
immunosuppression but not after thymectomy. Both in individual cases and in the whole
population, a correlation between Ab levels and disease severity was found.
The authors measured anti–muscle-specific tyrosine kinase (anti-MuSK) antibodies (Abs) in 83 serum samples from 40 patients and evaluated their correlation with myasthenia gravis severity and treatment response. Ab concentrations were often reduced by immunosuppression but not after thymectomy. Both in individual cases and in the whole population, a correlation between Ab levels and disease severity was found.
American Academy of Neurology