Variable results after rituximab in neuromyelitis optica

JW Lindsey, KM Meulmester, SA Brod, F Nelson… - Journal of the …, 2012 - Elsevier
Our objective was to assess the efficacy of rituximab (RTX) in neuromyelitis optica (NMO).
We conducted a retrospective review of cases personally treated by the authors. We
identified nine subjects meeting criteria for either NMO or recurrent longitudinally extensive
transverse myelitis (LETM) who were treated with RTX and documented their clinical course.
Six of the nine subjects continued to have relapses after RTX treatment. RTX was the first
immunosuppressive treatment used after diagnosis in five subjects, and four of these …