[HTML][HTML] MicroRNA126 contributes to granulocyte colony-stimulating factor-induced hematopoietic progenitor cell mobilization by reducing the expression of vascular …
O Salvucci, K Jiang, P Gasperini, D Maric, J Zhu… - …, 2012 - ncbi.nlm.nih.gov
O Salvucci, K Jiang, P Gasperini, D Maric, J Zhu, S Sakakibara, G Espigol-Frigole, S Wang…
Haematologica, 2012•ncbi.nlm.nih.govBackground Mobilization of hematopoietic stem/progenitor cells from the bone marrow to the
peripheral blood by granulocyte colony-stimulating factor is the primary means to acquire
stem cell grafts for hematopoietic cell transplantation. Since hematopoietic stem/progenitor
cells represent a minority of all blood cells mobilized by granulocyte colony-stimulating
factor, the underlying mechanisms need to be understood in order to develop selective
drugs.
peripheral blood by granulocyte colony-stimulating factor is the primary means to acquire
stem cell grafts for hematopoietic cell transplantation. Since hematopoietic stem/progenitor
cells represent a minority of all blood cells mobilized by granulocyte colony-stimulating
factor, the underlying mechanisms need to be understood in order to develop selective
drugs.
Abstract
Background
Mobilization of hematopoietic stem/progenitor cells from the bone marrow to the peripheral blood by granulocyte colony-stimulating factor is the primary means to acquire stem cell grafts for hematopoietic cell transplantation. Since hematopoietic stem/progenitor cells represent a minority of all blood cells mobilized by granulocyte colony-stimulating factor, the underlying mechanisms need to be understood in order to develop selective drugs.
ncbi.nlm.nih.gov