Elevated concentrations of exhaled hydrogen peroxide in asthmatic patients
A Emelyanov, G Fedoseev, A Abulimity, K Rudinski… - Chest, 2001 - Elsevier
Background Airway inflammation is important in the development and progression of
asthma. Activation of inflammatory cells induces a respiratory burst resulting in the
production of reactive oxygen species, such as H 2 O 2. The aim of this study was to
measure the concentration of H 2 O 2 in exhaled breath condensate and its correlation with
airway obstruction, airway hyperresponsiveness, and concentration of eosinophil cationic
protein (ECP) in serum in 70 steroid-naive, atopic patients with unstable asthma (20 men; …
asthma. Activation of inflammatory cells induces a respiratory burst resulting in the
production of reactive oxygen species, such as H 2 O 2. The aim of this study was to
measure the concentration of H 2 O 2 in exhaled breath condensate and its correlation with
airway obstruction, airway hyperresponsiveness, and concentration of eosinophil cationic
protein (ECP) in serum in 70 steroid-naive, atopic patients with unstable asthma (20 men; …