Superoxide dismutase 3 attenuates experimental Th2-driven allergic conjunctivitis
HJ Lee, BM Kim, S Shin, TY Kim, SH Chung - Clinical Immunology, 2017 - Elsevier
Allergic conjunctivitis is an inflammatory eye disease mediated by Th2 type immune
response. The role of extracellular superoxide dismutase 3 (SOD3) in immune response and
allergic conjunctival inflammation was examined in a murine model for experimental allergic
conjunctivitis (EAC). Allergic conjunctivitis was induced in mice by allergen challenge with
ovalbumin in alum via the conjunctival sac. SOD3 was topically applied and allergy
indicators were compared. Clinical signs associated with conjunctivitis, such as OVA …
response. The role of extracellular superoxide dismutase 3 (SOD3) in immune response and
allergic conjunctival inflammation was examined in a murine model for experimental allergic
conjunctivitis (EAC). Allergic conjunctivitis was induced in mice by allergen challenge with
ovalbumin in alum via the conjunctival sac. SOD3 was topically applied and allergy
indicators were compared. Clinical signs associated with conjunctivitis, such as OVA …