There is ample evidence that allergic disorders, such as asthma, rhinitis, and atopic
dermatitis, are mediated by oxidative stress. Excessive exposure to reactive oxygen and
nitrogen species is the hallmark of oxidative stress and leads to damage of proteins, lipids,
and DNA. Oxidative stress occurs not only as a result of inflammation but also from
environmental exposure to air pollution and cigarette smoke. The specific localization of
antioxidant enzymes in the lung and the rapid reaction of nitric oxide with reactive oxygen …