Noncanonical Wnt11 signaling and cardiomyogenic differentiation
MP Flaherty, B Dawn - Trends in cardiovascular medicine, 2008 - Elsevier
Although the molecular details remain unclear, Wnt signaling via both canonical and
noncanonical pathways is integral to cardiac specification and morphogenesis. A growing
body of evidence also suggests substantial overlap between these supposedly discrete
pathways in cell-and context-dependent manners. The ability of Wnt11 to induce
cardiomyogenesis both during embryonic development and in adult cells makes it an
attractive candidate for preprogramming cells for cardiac repair. This review primarily …
noncanonical pathways is integral to cardiac specification and morphogenesis. A growing
body of evidence also suggests substantial overlap between these supposedly discrete
pathways in cell-and context-dependent manners. The ability of Wnt11 to induce
cardiomyogenesis both during embryonic development and in adult cells makes it an
attractive candidate for preprogramming cells for cardiac repair. This review primarily …