The histopathology of Sjögren's syndrome in labial salivary gland biopsies

JS Greenspan, TE Daniels, N Talal… - Oral Surgery, Oral …, 1974 - Elsevier
Labial salivary gland biopsy specimens from seventy-five patients evaluated for Sjögren's
syndrome were examined histologically. Clinically severe cases of Sjögren's syndrome
showed the most marked histologic change. Focus score was found to be the most useful
histologic index of severity of the disease. Large numbers of plasma cells were found in
small foci and mild cases. Plasma cells were decreased in proportion, compared to
lymphocytes, in larger foci and severe cases. These observations are discussed in the light …