A quantitative study of hair growth using mouse and rat vibrissal follicles: I. Dermal papilla volume determines hair volume

L Ibrahim, EA Wright - Development, 1982 - journals.biologists.com
L Ibrahim, EA Wright
Development, 1982journals.biologists.com
The volumes of the dermal papilla, matrix and fully grown hair of vibrissal follicles of rats and
mice were measured. Dermal papillae were surgically removed from rats' vibrissal follicles
and a small new dermal papilla was always reformed. The lower third of rats and mice
follicles, containing the whole of the dermal papilla was amputated and very small dermal
papillae were reformed. Follicles containing small dermal papillae produced small hairs and
a constant positive linear relationship of 7· 0 was found between the volume of the dermal …
Abstract
The volumes of the dermal papilla, matrix and fully grown hair of vibrissal follicles of rats and mice were measured.
Dermal papillae were surgically removed from rats’ vibrissal follicles and a small new dermal papilla was always reformed. The lower third of rats and mice follicles, containing the whole of the dermal papilla was amputated and very small dermal papillae were reformed.
Follicles containing small dermal papillae produced small hairs and a constant positive linear relationship of 7·0 was found between the volume of the dermal papilla and the volume of the full-grown hair for all cases studied.
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