Quantitative analysis of brain perfusion SPECT in Alzheimer's disease using a fully automated regional cerebral blood flow quantification software, 3DSRT
S Kobayashi, M Tateno, K Utsumi, A Takahashi… - Journal of the …, 2008 - Elsevier
PURPOSE: The clinical symptoms of Alzheimer's disease (AD) show great diversity
depending on the clinical stage. We investigated the correlation of regional cerebral blood
flow (rCBF) changes and the clinical severity of AD patients. METHODS: Thirty-nine AD
patients and 16 normal subjects participated in this study. AD patients were divided into
three subgroups by clinical severity. Quantitative brain perfusion SPECT analyses were
performed using a rCBF quantification software, 3DSRT. RESULTS: In mild AD, significant …
depending on the clinical stage. We investigated the correlation of regional cerebral blood
flow (rCBF) changes and the clinical severity of AD patients. METHODS: Thirty-nine AD
patients and 16 normal subjects participated in this study. AD patients were divided into
three subgroups by clinical severity. Quantitative brain perfusion SPECT analyses were
performed using a rCBF quantification software, 3DSRT. RESULTS: In mild AD, significant …