[PDF][PDF] Amyloid-β is found in drusen from some age-related macular degeneration retinas, but not in drusen from normal retinas

T Dentchev, AH Milam, VMY Lee… - American journal of …, 2003 - molvis.org
T Dentchev, AH Milam, VMY Lee, JQ Trojanowski, JL Dunaief
American journal of ophthalmology, 2003molvis.org
METHODS Source of tissue and population profile: Most post mortem eyes were obtained
through the Foundation Fighting Blindness (FFB) eye donor program. The eye pathology
reports provided the patient age, gender, brief ocular and medical history, cause of death,
and post mortem interval. A few eyes were obtained directly from eye banks. One donor had
a potentially relevant co-morbid condition; patient 99-35 had insulin-dependent diabetes
mellitus (but no Aβ-positive vesicles). The histopathologic studies followed the tenets of the …
METHODS
Source of tissue and population profile: Most post mortem eyes were obtained through the Foundation Fighting Blindness (FFB) eye donor program. The eye pathology reports provided the patient age, gender, brief ocular and medical history, cause of death, and post mortem interval. A few eyes were obtained directly from eye banks. One donor had a potentially relevant co-morbid condition; patient 99-35 had insulin-dependent diabetes mellitus (but no Aβ-positive vesicles). The histopathologic studies followed the tenets of the Declaration of Helsinki, and informed consent was obtained from all eye donors ante mortem. Approval for research on human post mortem donor eyes was obtained from the University of Pennsylvania.
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