[HTML][HTML] Regulation of TGF-β receptor activity
F Huang, YG Chen - Cell & bioscience, 2012 - Springer
F Huang, YG Chen
Cell & bioscience, 2012•SpringerTGF-β signaling regulates diverse cellular processes, including cell proliferation,
differentiation, apoptosis, cell plasticity and migration. Its dysfunctions can result in various
kinds of diseases, such as cancer and tissue fibrosis. TGF-β signaling is tightly regulated at
different levels along the pathway, and modulation of TGF-β receptor activity is a critical step
for signaling regulation. This review focuses on our recent understanding of regulation of
TGF-β receptor activity.
differentiation, apoptosis, cell plasticity and migration. Its dysfunctions can result in various
kinds of diseases, such as cancer and tissue fibrosis. TGF-β signaling is tightly regulated at
different levels along the pathway, and modulation of TGF-β receptor activity is a critical step
for signaling regulation. This review focuses on our recent understanding of regulation of
TGF-β receptor activity.
Abstract
TGF-β signaling regulates diverse cellular processes, including cell proliferation, differentiation, apoptosis, cell plasticity and migration. Its dysfunctions can result in various kinds of diseases, such as cancer and tissue fibrosis. TGF-β signaling is tightly regulated at different levels along the pathway, and modulation of TGF-β receptor activity is a critical step for signaling regulation. This review focuses on our recent understanding of regulation of TGF-β receptor activity.
Springer