Infantile generalized pustular psoriasis associated with lytic lesions of the bone

RA Ivker, CM Grin‐Jorgensen, VK Vega… - Pediatric …, 1993 - Wiley Online Library
RA Ivker, CM Grin‐Jorgensen, VK Vega, DM Hoss, JM Grant‐Kels
Pediatric dermatology, 1993Wiley Online Library
Generalized pustular psoriasis is rare in children, especially in those less than 1 year of age.
Lytic lesions of the bone have been reported in children with psoriasis, but are rare. We
describe an infant with the clinical and histopathologic features of generalized pustular
psoriasis that began in the first few weeks of life. In addition, this patient had sterile lytic
lesions of the bone. Despite significant improvement In the bone lesions, his skin condition
was resistant to therapy.
Abstract
Generalized pustular psoriasis is rare in children, especially in those less than 1 year of age. Lytic lesions of the bone have been reported in children with psoriasis, but are rare. We describe an infant with the clinical and histopathologic features of generalized pustular psoriasis that began in the first few weeks of life. In addition, this patient had sterile lytic lesions of the bone. Despite significant improvement In the bone lesions, his skin condition was resistant to therapy.
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