DIRA, DITRA, and new insights into pathways of skin inflammation: what's in a name?
EW Cowen, R Goldbach-Mansky - Archives of dermatology, 2012 - jamanetwork.com
DERMATOLOGY HAS A LONG-STANDING AF-finity for acronyms. From AGEP (acute
generalized exanthematous pustulosis) to XP (xeroderma pigmentosum), acronyms have
become a part of our dermatology lexicon, perhaps occasionally to the consternation of our
colleagues in other specialties. In this issue, Brau-Javier et al1 describe a patient with a
severe pustular skin disease called “DIRA”—an acronym for “deficiency of the interleukin 1
(IL-1) receptor antagonist,” which we first described in 9 pediatric patients in 2009. 2 As its …
generalized exanthematous pustulosis) to XP (xeroderma pigmentosum), acronyms have
become a part of our dermatology lexicon, perhaps occasionally to the consternation of our
colleagues in other specialties. In this issue, Brau-Javier et al1 describe a patient with a
severe pustular skin disease called “DIRA”—an acronym for “deficiency of the interleukin 1
(IL-1) receptor antagonist,” which we first described in 9 pediatric patients in 2009. 2 As its …