A human papillomavirus–associated disease with disseminated warts, depressed cell-mediated immunity, primary lymphedema, and anogenital dysplasia: WILD …

A Kreuter, B Hochdorfer, NH Brockmeyer… - Archives of …, 2008 - jamanetwork.com
Background Epidermodysplasia verruciformis (EV) is a rare genodermatosis associated with
infections with specific human papillomaviruses (HPVs) belonging to the β genus of HPV.
Patients with EV usually have a selective defect in cell-mediated immunity. Although skin
cancer frequently develops in the sun-exposed cutaneous lesions of patients with EV, the
anogenital area is usually not affected by squamous cell carcinomas related to mucosal
HPV types. Observations We report the case of a patient with clinical similarities to EV who …