Relapses Requiring Intravenous Steroid Use and Multiple-Sclerosis–related Hospitalizations: Integrated Analysis of the Delayed-release Dimethyl Fumarate Phase III …
Purpose The purpose was to report the effects of delayed-release dimethyl fumarate (DMF;
also known as gastro-resistant DMF) on the number of relapses requiring intravenous (IV)
steroids and multiple sclerosis (MS)-related hospitalizations using integrated data from the
Phase III DEFINE and CONFIRM studies. Methods DEFINE and CONFIRM were
randomized, double-blind, placebo-controlled, multicenter studies that evaluated the efficacy
and safety of DMF over a 2-year period in patients with relapsing-remitting MS (RRMS) …
also known as gastro-resistant DMF) on the number of relapses requiring intravenous (IV)
steroids and multiple sclerosis (MS)-related hospitalizations using integrated data from the
Phase III DEFINE and CONFIRM studies. Methods DEFINE and CONFIRM were
randomized, double-blind, placebo-controlled, multicenter studies that evaluated the efficacy
and safety of DMF over a 2-year period in patients with relapsing-remitting MS (RRMS) …
