Induction and evasion of type I interferon responses by influenza viruses
A Garcia-Sastre - Virus research, 2011 - Elsevier
Influenza A and B viruses are a major cause of respiratory disease in humans. In addition,
influenza A viruses continuously re-emerge from animal reservoirs into humans causing
human pandemics every 10–50 years of unpredictable severity. Among the first lines of
defense against influenza virus infection, the type I interferon (IFN) response plays a major
role. In the last 10 years, there have been major advances in understanding how cells
recognize being infected by influenza viruses, leading to secretion of type I IFN, and on the …
influenza A viruses continuously re-emerge from animal reservoirs into humans causing
human pandemics every 10–50 years of unpredictable severity. Among the first lines of
defense against influenza virus infection, the type I interferon (IFN) response plays a major
role. In the last 10 years, there have been major advances in understanding how cells
recognize being infected by influenza viruses, leading to secretion of type I IFN, and on the …