Vascular endothelial growth factor in bronchoalveolar lavage from normal subjects and patients with diffuse parenchymal lung disease

KC Meyer, A Cardoni, ZZ Xiang - Journal of Laboratory and Clinical …, 2000 - Elsevier
Vascular endothelial growth factor (VEGF) is a potent angiogenic agent that is expressed by
epithelial cells in the mature lung of various animal species. We hypothesized that VEGF
levels in lower respiratory tract secretions may vary with age or with lung inflammation in
human beings. We measured VEGF165 in bronchoalveolar lavage fluid (BALF) from normal
volunteers (NVs) of varying age and from patients with cystic fibrosis (CF), sarcoidosis, or
idiopathic pulmonary fibrosis (IPF). A considerable gradient in VEGF levels was found with …